Ontology highlight
ABSTRACT:
SUBMITTER: Marra A
PROVIDER: S-EPMC7568552 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Marra Antonio A Trapani Dario D Viale Giulia G Criscitiello Carmen C Curigliano Giuseppe G
NPJ breast cancer 20201016
Triple-negative breast cancer (TNBC) is not a unique disease, encompassing multiple entities with marked histopathological, transcriptomic and genomic heterogeneity. Despite several efforts, transcriptomic and genomic classifications have remained merely theoretic and most of the patients are being treated with chemotherapy. Driver alterations in potentially targetable genes, including PIK3CA and AKT, have been identified across TNBC subtypes, prompting the implementation of biomarker-driven the ...[more]