Intrauterine Exposure to Biologics in Inflammatory Autoimmune Diseases: A Systematic Review.

ABSTRACT:

Background

Inflammatory autoimmune diseases are chronic diseases that often affect women of childbearing age. Therefore, detailed knowledge of the safety profile of medications used for management of inflammatory autoimmune diseases during pregnancy is important. However, in many cases the potential harmful effects of medications (especially biologics) during pregnancy (and lactation) on mother and child have not been fully identified.

Objective

Our aim was to update the data on the occurrence of miscarriages and (major) congenital malformations when using biologics during pregnancy based on newly published articles. Additionally, we selected several different secondary outcomes that may be of interest for clinicians, especially information on adverse events in the use of a

SUBMITTER: Ghalandari N 

PROVIDER: S-EPMC7568712 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature