Distant Metastases in Patients with Intrahepatic Cholangiocarcinoma: Does Location Matter? A Retrospective Analysis of 370 Patients.

ABSTRACT:

Background

Intrahepatic cholangiocarcinoma (ICC) is an aggressive tumor entity, and distant metastases are common. However, studies investigating patterns and clinical relevance of distant metastases are rare. Therefore, we aimed to analyze occurrence, location, and prognostic impact of distant metastases on overall survival (OS).

Methods

Between 1997 and 2018, 417 patients with ICC were treated at our tertiary care center. Distant metastases and intrahepatic tumor burden were retrospectively evaluated in a longitudinal approach using volumetric assessment of cross-sectional imaging studies and all available medical/histopathological reports.

Results

Finally, 370 patients with histopathologically confirmed ICC were included. Of these, 186 showed distant metastases, ei

SUBMITTER: Hahn F 

PROVIDER: S-EPMC7569461 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature