Miliary Sarcoidosis: does it exist? A case series and systematic review of literature.

ABSTRACT:

Background and objectives

Sarcoidosis typically presents with peribronchovascular and perilymphatic nodules on high-resolution computed tomography (HRCT); a miliary pattern is reported but not well described.

Design setting

We describe four patients with miliary sarcoidosis and results of a systematic review of all previously reported cases from 1985 onwards.

Results

We identified only 27 cases of "miliary" sarcoidosis in the HRCT era. These patients were older (85.2% older than 40 years), had more co-morbidities (72.7%) and were symptomatic compared to "typical" sarcoidosis. Respiratory symptoms were present in 61.9% at diagnosis. Hypercalcemia was seen in 28.5%. On review of HRCT images, only 34.6% (9/26) had a "true miliary" pattern without fissural nodules. In our

SUBMITTER: Rajagopala S 

PROVIDER: S-EPMC7569537 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature