Incidence, comorbidity and mortality in patients with necrotising soft-tissue infections, 2005-2018: a Danish nationwide register-based cohort study.

ABSTRACT:

Objective

To assess the incidence, comorbidities, treatment modalities and mortality in patients with necrotising soft-tissue infections (NSTIs) in Denmark.

Design

Nationwide population-based registry study.

Setting

Denmark.

Participants

Danish residents with NSTI between 1 January 2005 and 31 August 2018.

Main outcome measure

Incidence of disease per 100 000 person/year and all-cause mortality at day 90 obtained from Danish National Patient Registry and the Danish Civil Registration System.

Results

1527 patients with NSTI were identified, yielding an incidence of 1.99 per 100 000 person/year. All-cause 30-day, 90-day and 1-year mortality were 19.4% (95% CI 17.4% to 21.5%), 25.2% (95% CI 23.1% to 27.5%) and 30.4% (95% CI 28.0% to 32.8%), respectiv

SUBMITTER: Hedetoft M 

PROVIDER: S-EPMC7569942 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature