Age-dependent seroprevalence of dengue and chikungunya: inference from a cross-sectional analysis in Esmeraldas Province in coastal Ecuador.

ABSTRACT:

Objectives

There are few population-based estimates for prevalence of past exposure to dengue and chikungunya viruses despite common epidemiological features. Here, we have developed a novel statistical method to study patterns of age-dependent prevalence of immunity in a population following exposures to two viruses which share similar epidemiological features including mode of transmission and induction of long-lasting immunity. This statistical technique accounted for sociodemographic characteristics associated with individuals and households.

Settings

The data consist of a representative sample from an ongoing longitudinal birth cohort set-up in a tropical district in coastal Ecuador (Esmeraldas).

Participants

We collected data and blood samples from 319 individua

SUBMITTER: Chis Ster I 

PROVIDER: S-EPMC7569951 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature