Patient-ventilator asynchrony in acute brain-injured patients: a prospective observational study.

ABSTRACT:

Background

Patient-ventilator asynchrony is common in mechanically ventilated patients and may be related to adverse outcomes. Few studies have reported the occurrence of asynchrony in brain-injured patients. We aimed to investigate the prevalence, type and severity of patient-ventilator asynchrony in mechanically ventilated patients with brain injury.

Methods

This prospective observational study enrolled acute brain-injured patients undergoing mechanical ventilation. Esophageal pressure monitoring was established after enrollment. Flow, airway pressure, and esophageal pressure-time waveforms were recorded for a 15-min interval, four times daily for 3 days, for visually detecting asynchrony by offline analysis. At the end of each dataset recording, the respiratory drive was

SUBMITTER: Luo XY 

PROVIDER: S-EPMC7570406 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature