Association between Kawasaki Disease and Prenatal Exposure to Ambient and Industrial Air Pollution: A Population-Based Cohort Study.

ABSTRACT:

Background

Environmental factors may contribute to the development of Kawasaki disease in children, but prenatal environmental exposures are understudied.

Objective

We used a population-based cohort to investigate whether prenatal exposure to outdoor air pollution is associated with the incidence of Kawasaki disease in childhood.

Methods

We performed a longitudinal cohort study of all children born in Quebec, Canada, between 2006 and 2012. Children were followed for Kawasaki disease from birth until 31 March 2018. We assigned prenatal air pollutant exposure according to the residential postal code at birth. The main exposure was annual average concentration of ambient fine particulate matter [PM ≤2.5μm in aerodynamic diameter (PM2.5) and nitrogen dioxide (NO2) from sa

SUBMITTER: Buteau S 

PROVIDER: S-EPMC7571626 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature