Local staging and treatment in extremity rhabdomyosarcoma. A report from the EpSSG-RMS2005 study.

ABSTRACT: Rhabdomyosarcoma of the extremities present with two main challenges: correct evaluation of initial regional nodal involvement and define adequate local treatment.

Methods

Pediatric patients with localized rhabdomyosarcoma of the extremity included in the EpSSG-RMS2005 study between 2005 and 2014 were evaluated for staging, treatment, and survival. The outcome was compared to the preceding European SIOP-MMT studies.

Results

Of the 162 patients included, histology was unfavorable in 113 (70%), 124 (77%) were younger than 10 years, 128 (79%) were IRS III, and 47 (29%) were node-positive. A regional node biopsy was performed in 97 patients (60%) and modified the lymph node stage in 15/97 (16%). Primary and delayed surgery was performed in 155 (96%) and radiotherapy delivered in

SUBMITTER: Terwisscha van Scheltinga SEJ 

PROVIDER: S-EPMC7571832 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature