Controlling the behaviour of Drosophila melanogaster via smartphone optogenetics.

ABSTRACT: Invertebrates such as Drosophila melanogaster have proven to be a valuable model organism for studies of the nervous system. In order to control neuronal activity, optogenetics has evolved as a powerful technique enabling non-invasive stimulation using light. This requires light sources that can deliver patterns of light with high temporal and spatial precision. Currently employed light sources for stimulation of small invertebrates, however, are either limited in spatial resolution or require sophisticated and bulky equipment. In this work, we used smartphone displays for optogenetic control of Drosophila melanogaster. We developed an open-source smartphone app that allows time-dependent display of light patterns and used this to activate and inhibit different neuronal populations in both

SUBMITTER: Meloni I 

PROVIDER: S-EPMC7572528 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature