Acute Alcohol Intake Produces Widespread Decreases in Cortical Resting Signal Variability in Healthy Social Drinkers.

ABSTRACT:

Background

Acute alcohol intoxication has wide-ranging neurobehavioral effects on psychomotor, attentional, inhibitory, and memory-related cognitive processes. These effects are mirrored in disruption of neural metabolism, functional activation, and functional network coherence. Metrics of intraregional neural dynamics such as regional signal variability (RSV) and brain entropy (BEN) may capture unique aspects of neural functional capacity in healthy and clinical populations; however, alcohol's influence on these metrics is unclear. The present study aimed to elucidate the influence of acute alcohol intoxication on RSV and to clarify these effects with subsequent BEN analyses.

Methods

26 healthy adults between 25 and 45 years of age (65.4% women) participated in 2 counterbal

SUBMITTER: Sevel L 

PROVIDER: S-EPMC7572592 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature