Neighborhood deprivation, prefrontal morphology and neurocognition in late childhood to early adolescence.

ABSTRACT:

Background

Neighborhood deprivation adversely effects neurodevelopment and cognitive function; however, mechanisms remain unexplored. Neighborhood deprivation could be particularly impactful in late childhood/early adolescence, in neural regions with protracted developmental trajectories, e.g., prefrontal cortex (PFC).

Methods

The Adolescent Brain Cognitive Development (ABCD) study recruited 10,205 youth. Geocoded residential history was used to extract individual neighborhood characteristics. A general cognitive ability index and MRI scans were completed. Associations with neurocognition were examined. The relation of PFC surface area and cortical thickness to neighborhood deprivation was tested. PFC subregions and asymmetry, with putative differential environmental suscept

SUBMITTER: Vargas T 

PROVIDER: S-EPMC7572635 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature