Alternative type 2 diabetes screening tests may reduce the number of U.S. adults with undiagnosed diabetes.

ABSTRACT:

Aim

To evaluate the U.S. population-level impact of two alternatives for initial type 2 diabetes screening [opportunistic random plasma glucose (RPG) > 6.7 mmol/l and a 1-h 50-g glucose challenge test (GCT) > 8.9 mmol/l] compared with American Diabetes Association (ADA)-recommended tests.

Methods

Using a sample (n = 1471) from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 that represented 145 million U.S. adults at high risk for developing type 2 diabetes, we simulated a two-test screening process. We compared ADA-recommended screening tests [fasting plasma glucose (FPG), 2-h 75-g oral glucose tolerance test (OGTT), HbA_1c ] vs. initial screening with opportunistic RPG or GCT (followed by FPG, OGTT or HbA_1c ). After simulation,

SUBMITTER: Dadwani RS 

PROVIDER: S-EPMC7572743 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature