Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV.

ABSTRACT:

Background

Frailty and physical function impairments occur at an earlier than expected age in people with HIV (PWH). The goal of this study was to determine which tools or combination of tools assessing frailty/physical function were most predictive of mortality in a middle-aged population of PWH.

Methods

Using electronic health records, we determined survival, death, or loss to follow-up for 359 PWH, aged 45-65 years originally enrolled in a 2009-2010 cross-sectional cohort study. The predictive accuracy of various physical function measures [frailty score, Veterans Aging Cohort Study (VACS) index, 400-m walk, Short Physical Performance Battery (SPPB), grip strength, and falls] were compared using integrated time-dependent receiver operating characteristic area under the cu

SUBMITTER: Pelloquin R 

PROVIDER: S-EPMC7572796 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature