White Matter Hyperintensities Predict Response to Language Treatment in Poststroke Aphasia.

ABSTRACT:

Background

White matter hyperintensities (WMH) are a radiological marker of brain health that has been associated with language status in poststroke aphasia; however, its association with language treatment outcomes remains unknown.

Objective

To determine whether WMH in the right hemisphere (RH) predict response to language therapy independently from demographics and stroke lesion-related factors in poststroke aphasia.

Methods

We used the Fazekas scale to rate WMH in the RH in 30 patients with poststroke aphasia who received language treatment. We developed ordinal regression models to examine language treatment effects as a function of WMH severity after controlling for aphasia severity, stroke lesion volume, time post onset, age, and education level. We also evaluat

SUBMITTER: Varkanitsa M 

PROVIDER: S-EPMC7572835 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature