Risk of Renal Failure Within 10 or 20 Years of Systemic Lupus Erythematosus Diagnosis.

ABSTRACT:

Objective

The frequency of endstage renal disease (ESRD) from systemic lupus erythematosus (SLE) in the United States has not improved over the last few decades in large population datasets. Understanding the risk factors for renal failure in SLE could lead to earlier detection of lupus nephritis and potentially more effective treatments in those with markers of poor prognosis.

Methods

The Hopkins Lupus Cohort, comprising 2528 patients was used. One hundred fifty-one patients experienced renal failure after SLE diagnosis, defined as dialysis or renal transplant. We estimated the risk of renal failure in subgroups defined by demographics, laboratory tests, and the American College of Rheumatology/Systemic Lupus International Collaborating Clinics (ACR/SLICC) classification cr

SUBMITTER: Petri M 

PROVIDER: S-EPMC7572868 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature