Cortical and subcortical functional specificity associated with response inhibition.

ABSTRACT: Is motor response inhibition supported by a specialised neuronal inhibitory control mechanism, or by a more general system of action updating? This pre-registered study employed a context-cueing paradigm requiring both inhibitory and non-inhibitory action updating in combination with functional magnetic resonance imaging to test the specificity of responses under different updating conditions, including the cancellation of actions. Cortical regions of activity were found to be common to multiple forms of action updating. However, functional specificity during response inhibition was observed in the anterior right inferior frontal gyrus. In addition, fronto-subcortical activity was explored using a novel contrast method. These exploratory results indicate that the specificity for response i

SUBMITTER: Maizey L 

PROVIDER: S-EPMC7573537 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature