The Importance of Verification CT-QA Scans in Patients Treated with IMPT for Head and Neck Cancers.

ABSTRACT:

Purpose

To understand how verification computed tomography-quality assurance (CT-QA) scans influenced clinical decision-making to replan patients with head and neck cancer and identify predictors for replanning to guide intensity-modulated proton therapy (IMPT) clinical practice.

Patients and methods

We performed a quality-improvement study by prospectively collecting data on 160 consecutive patients with head and neck cancer treated using spot-scanning IMPT who underwent weekly verification CT-QA scans. Kaplan-Meier estimates were used to determine the cumulative probability of a replan by week. Predictors for replanning were determined with univariate (UVA) and multivariate (MVA) Cox model hazard ratios (HRs). Logistic regression was used to determine odds ratios (ORs).

SUBMITTER: Evans JD 

PROVIDER: S-EPMC7574830 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature