Xanthene based hybrid analogues to inhibit protease of novel corona Virus: Molecular docking and ADMET studies.

ABSTRACT: In December 2019, the SARS-CoV-2 was reported for the first time and the infected person is reported at Wuhan, China. Till date, about twenty four million people around the world are infected due to the SARS-CoV-2. The structure of this corona virus is new and different from other corona viruses. The genome has a positive sense single RNA strand and it is responsible for the encoding of the protein. The protease of the SARS-CoV-2 is responsible for the cleavage and therefore, it should be targeted to develop medicine. Till date, no medicine or vaccine is in the market to cure from the infection. Researchers around the world are working on the development of efficacious and safe vaccine/ drug to cure from the infection. Therefore, the authors used previously synthesized compounds, xanthene-

SUBMITTER: Kumar Vishvakarma V 

PROVIDER: S-EPMC7575443 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature