Benefit-Risk Assessment of Vaccines. Part I: A Systematic Review to Identify and Describe Studies About Quantitative Benefit-Risk Models Applied to Vaccines.

ABSTRACT:

Introduction

Understanding the balance between the benefits and risks of vaccination is essential to ensure informed and adequate public health decision making. Quantitative benefit-risk models (qBRm) represent useful tools to help decision makers with supporting benefit-risk assessment throughout the lifecycle of a medical product. However, few initiatives have been launched to harmonise qBRm approaches, specifically for vaccines.

Objectives

The aim of this paper was to identify publications about qBRm applied to vaccines through a systematic literature review, and to describe their characteristics.

Methods

Medline, Scopus and Institute for Scientific Information Web of Knowledge databases were searched to identify articles in English, published from database incepti

SUBMITTER: Arlegui H 

PROVIDER: S-EPMC7575467 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature