Analysis of preoperative circulating tumor cells for recurrence in patients with hepatocellular carcinoma after liver transplantation.

ABSTRACT:

Background

Liver transplantation (LT) is an effective option for hepatocellular carcinoma (HCC) and end-stage liver cirrhosis. However, organ shortage and tumor recurrence are the main obstacles limiting its popularization and application in HCC patients. Testing for circulating tumor cells (CTCs) would be a valuable strategy to predict the recurrence and metastasis of HCC after LT. Various CTCs detection methods have different advantages and disadvantages. This study aims to investigate the predictive value of testing for CTCs based on immunofluorescence in situ hybridization of peripheral blood cells in patients with HCC after LT.

Methods

A total of 50 patients who received testing for CTCs and then underwent LT were enrolled in this study. Negative enrichment and immunofl

SUBMITTER: Chen Z 

PROVIDER: S-EPMC7575976 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature