The utilization of aerosol therapy in mechanical ventilation patients: a prospective multicenter observational cohort study and a review of the current evidence.

ABSTRACT:

Background

Aerosol delivery via mechanical ventilation has been reported to vary significantly among different intensive care units (ICU). The optimal technique for using each aerosol generator may need to be updated with the available evidence.

Methods

A 2-week prospective multicenter observational cohort study was implemented to record aerosol delivery for mechanically ventilated adult patients in Chinese ICUs. Our data included the type of aerosol device and its placement, ventilator type, humidification, and aerosolized medication administered. A guide for the optimal technique for aerosol delivery during mechanical ventilation was summarized after a thorough literature review.

Results

A total of 160 patients (105 males) from 28 ICUs were enrolled, of whom 125 (78

SUBMITTER: Lyu S 

PROVIDER: S-EPMC7575997 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature