Application of an elevated plasma D-dimer cut-off value improves prognosis prediction of advanced non-small cell lung cancer.

ABSTRACT:

Background

Tumor-related coagulation dysfunction has been reported to be closely associated with poor prognosis. The present study is aimed to evaluate the prognostic prediction of an elevated plasma D-dimer cut-off value in advanced non-small cell lung cancer (NSCLC).

Methods

A total of 233 patients initially diagnosed with advanced NSCLC were retrospectively analyzed, an elevated plasma cut-off value 981 ng/mL of D-dimer, which was instead of the clinical cut-off value 500 mg/mL, was used to determine the high and low. Univariate analysis using the Kaplan-Meier method and log-ranking test, and the multivariate analysis using the Cox proportional hazard regression model were performed.

Results

Results showed when using the D-dimer value of 500 ng/mL as an evaluation

SUBMITTER: Chen C 

PROVIDER: S-EPMC7576026 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature