Diagnostic and prognostic value of HABP2 as a novel biomarker for endometrial cancer.

ABSTRACT:

Background

Endometrial cancer is the fifth most common malignant disorder in women, with its incidence increasing. A biomarker with diagnostic and prognostic value remains to be found. The HABP2 protein, or Factor VII-activating protease, encodes a hyaluronic acid-binding protein.

Methods

Patient data including clinical characteristics and RNAseq information of HABP2 was obtained from The Cancer Genome Atlas (TCGA), and analyzed by R statistic packages. A total of 370 women with endometrial cancer were enrolled in the study. To study the diagnostic value of HABP2 in patients with endometrial cancer, receiver operating characteristic (ROC) curves were plotted by the pROC package. To study the prognostic value of HABP2 in patients with endometrial cancer, the survival package

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC7576057 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature