Surface-based morphometry study of the brain in benign childhood epilepsy with centrotemporal spikes.

ABSTRACT:

Background

The study aimed to explore cortical morphology in benign childhood epilepsy with centrotemporal spikes (BECTS) and the relationship between cortical characteristics and age of onset and intelligence quotient (IQ).

Methods

Cortical morphometry with surface-based morphometry (SBM) was used to compare changes in cortical thickness, gyrification, sulcal depth, and fractal dimension of the cerebral cortex between 25 BECTS patients and 20 healthy controls (HCs) with two-sample t-tests [P<0.05, family-wise error (FWE) corrected]. Relationships between abnormal cortical morphological changes and age of onset and IQ, which included verbal intelligence quotient (VIQ), performance intelligence quotient (PIQ), and full-scale intelligence quotient (FIQ) were investigate

SUBMITTER: Li Z 

PROVIDER: S-EPMC7576069 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature