Risk factors for the critical illness in SARS-CoV-2 infection: a multicenter retrospective cohort study.

ABSTRACT:

Background

Prior studies reported that 5 ~ 32% COVID-19 patients were critically ill, a situation that poses great challenge for the management of the patients and ICU resources. We aim to identify independent risk factors to serve as prediction markers for critical illness of SARS-CoV-2 infection.

Methods

Fifty-two critical and 200 non-critical SARS-CoV-2 nucleic acid positive patients hospitalized in 15 hospitals outside Wuhan from January 19 to March 6, 2020 were enrolled in this study. Multivariable logistic regression and LASSO logistic regression were performed to identify independent risk factors for critical illness.

Results

Age older than 60 years, dyspnea, respiratory rate > 24 breaths per min, leukocytosis > 9.5 × 10⁹/L, neutrophilia > 6.3 × 10

SUBMITTER: Cheng S 

PROVIDER: S-EPMC7576549 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature