Development of an immunogenomic landscape for the competing endogenous RNAs network of peri-implantitis.

ABSTRACT:

Background

Peri-implantitis is an inflammation that occurs around the implant, resulting in varying degrees of inflammatory damage to the soft and hard tissues. The characteristic criterion is the loss of the supporting bone in an inflammatory environment. However, the specific mechanisms and biomarkers involved in peri-implantitis remain to be further studied. Recently, competing endogenous RNAs (ceRNA) and immune microenvironment have been found to play a more important role in the inflammatory process. In our study, we analyzed the expression of immune related microRNAs (miRNAs), long noncoding RNAs (lncRNAs) and message RNAs (mRNAs) in peri-implantitis by analyzing GSE33774 and GSE57631.

Methods

In this study, we explored the expression profile data of immune-related lnc

SUBMITTER: Li Y 

PROVIDER: S-EPMC7576812 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature