Multiple Vulnerabilities to Health Disparities and Incident Heart Failure Hospitalization in the REGARDS Study.

ABSTRACT:

Background

Socially determined vulnerabilities (SDVs) to health disparities often cluster within the same individual. SDVs are separately associated with increased risk of heart failure (HF). The objective of this study was to determine the cumulative effect of SDVs to health disparities on incident HF hospitalization.

Methods and results

Using the REGARDS (Reasons for Geographic and Racial Differences in Stroke) cohort study, we studied 25 790 participants without known HF and followed them for 10+ years. Our primary outcome was an incident HF hospitalization through December 31, 2016. Guided by the Healthy People 2020 framework for social determinants of health, we examined 10 potential SDVs. We retained SDVs associated with incident HF hospitalization (P<0.10) and

SUBMITTER: Pinheiro LC 

PROVIDER: S-EPMC7577176 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature