Physiological and quantitative CT-scan characterization of COVID-19 and typical ARDS: a matched cohort study.

ABSTRACT:

Purpose

To investigate whether COVID-19-ARDS differs from all-cause ARDS.

Methods

Thirty-two consecutive, mechanically ventilated COVID-19-ARDS patients were compared to two historical ARDS sub-populations 1:1 matched for PaO₂/FiO₂ or for compliance of the respiratory system. Gas exchange, hemodynamics and respiratory mechanics were recorded at 5 and 15 cmH₂O PEEP. CT scan variables were measured at 5 cmH₂O PEEP.

Results

Anthropometric characteristics were similar in COVID-19-ARDS, PaO₂/FiO₂-matched-ARDS and Compliance-matched-ARDS. The PaO₂/FiO₂-matched-ARDS and COVID-19-ARDS populations (both with PaO₂/FiO₂ 106 ± 59 mmHg) had different respiratory system com

SUBMITTER: Chiumello D 

PROVIDER: S-EPMC7577365 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature