The relationship between advanced glycation end products and gestational diabetes: A systematic review and meta-analysis.

ABSTRACT:

Introduction

Gestational Diabetes Mellitus (GDM) is a condition in which women without history of diabetes experience hyperglycemia during pregnancy, especially at the second and third trimesters. In women who have had GDM, an elevated body mass index (BMI) may have a substantial impact for persistent hyperglycemia in their lives after gestation. Beyond hyperglycemia, increased local oxidative stress directly promotes the formation of Advanced Glycation End-products (AGEs). Hence, this systematic review and meta-analysis was aimed to determine the relationship between the level of AGEs and/or related metabolic biomarkers with GDM.

Methods

Literature search was carried out through visiting electronic databases, indexing services, and directories including PubMed/MEDLINE (Ovid

SUBMITTER: Sisay M 

PROVIDER: S-EPMC7577486 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature