The level of antimicrobial resistance of sewage isolates is higher than that of river isolates in different Escherichia coli lineages.

ABSTRACT: The dissemination of antimicrobial-resistant bacteria in environmental water is an emerging concern in medical and industrial settings. Here, we analysed the antimicrobial resistance of Escherichia coli isolates from river water and sewage by the use of a combined experimental phenotypic and whole-genome-based genetic approach. Among the 283 tested strains, 52 were phenotypically resistant to one or more antimicrobial agents. The E. coli isolates from the river and sewage samples were phylogenetically indistinguishable, and the antimicrobial-resistant strains were dispersedly distributed in a whole-genome-based phylogenetic tree. The prevalence of antimicrobial-resistant strains as well as the number of antimicrobials to which they were resistant were higher in sewage samples than in river

SUBMITTER: Ogura Y 

PROVIDER: S-EPMC7578040 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature