Using patient-reported symptoms of dyspnea for screening reduced respiratory function in patients with motor neuron diseases.

ABSTRACT:

Background

Poor monitoring of respiratory function may lead to late initiation of non-invasive ventilation (NIV) in patients with motor neuron diseases (MND). Monitoring could be improved by remotely assessing hypoventilation symptoms between clinic visits. We aimed to determine which patient-reported hypoventilation symptoms are best for screening reduced respiratory function in patients with MND, and compared them to the respiratory domain of the amyotrophic lateral sclerosis functional rating scale (ALSFRS-R).

Methods

This prospective multi-center study included 100 patients with MND, who were able to perform a supine vital capacity test. Reduced respiratory function was defined as a predicted supine vital capacity ≤ 80%. We developed a 14-item hypoventilation symptom que

SUBMITTER: Helleman J 

PROVIDER: S-EPMC7578163 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature