Ontology highlight
ABSTRACT:
SUBMITTER: Roseweir AK
PROVIDER: S-EPMC7578335 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
The journal of pathology. Clinical research 20200513 4
Histological 'phenotypic subtypes' that classify patients into four groups (immune, canonical, latent and stromal) have previously been demonstrated to stratify survival in a stage I-III colorectal cancer (CRC) pilot cohort. However, clinical utility has not yet been validated. Therefore, this study assessed prognostic value of these subtypes in additional patient cohorts along with associations with risk of recurrence and response to chemotherapy. Two independent stage I-III CRC patient cohorts ...[more]