Active tuberculosis risk associated with malignancies: an 18-year retrospective cohort study in Korea.

ABSTRACT:

Background

Active tuberculosis (TB) develops in approximately 10% of people with a latent tuberculosis infection (LTBI). TB guidelines recommend that LTBI screening and treatments target high-risk patients. Malignancies are not universally considered a high-risk factor for active TB. This study aimed to determine the degrees to which active TB risk was associated with various cancers in a Korean population.

Methods

This study involved patients aged ≥20 years who were diagnosed with cancer at Ulsan University Hospital (UUH) from January 2000 to December 2014 and individuals who visited UUH for health screening and were age- and sex-matched randomly with cases in a 1:2 ratio. Using retrospective cohort study, the development of bacteriologically confirmed TB (BCTB) within 3 ye

SUBMITTER: Cheon J 

PROVIDER: S-EPMC7578502 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature