A Dual-Excitation Decoding Strategy Based on NIR Hybrid Nanocomposites for High-Accuracy Thermal Sensing.

ABSTRACT: Optical thermal sensing holds great promise for disease theranostics. However, traditional ratiometric thermometry methods, in which intensity ratio of two nonoverlapping emissions is defined as the thermosensitive parameter, may have a limited accuracy in temperature read-out due to the deleterious interference from wavelength- and temperature-dependent photon attenuation in tissue. To overcome this limitation, a dual-excitation decoding strategy based on NIR hybrid nanocomposites comprising self-assembled quantum dots (QDs) and Nd³⁺ doped fluoride nanocrystals (NCs) is proposed for thermal sensing. Upon excitation at 808 nm, the intensity ratio of two emissions at identical wavelength (1057 nm) from QDs and NCs, respectively, is defined as the thermometric parameter R.

SUBMITTER: Yu S 

PROVIDER: S-EPMC7578878 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature