Bronchiectasis and increased mortality in patients with corticosteroid-dependent severe asthma: a nationwide population study.

ABSTRACT:

Background

Long-term corticosteroid (CS) use is associated with increased mortality in patients with asthma, and comorbid bronchiectasis is also associated with frequent asthma exacerbation and increased healthcare use. However, there is limited information on whether bronchiectasis further increases mortality in patients with CS-dependent asthma. This study examined the impact of bronchiectasis on mortality in patients with CS-dependent asthma.

Methods

A retrospective cohort of patients with CS-dependent asthma ⩾18 years old was established using records from the Korean National Health Insurance Service database from 2005 to 2015. Patients with CS-dependent asthma with and without bronchiectasis were matched by age, sex, type of insurance, and Charlson comorbidity index. We

SUBMITTER: Choi H 

PROVIDER: S-EPMC7580190 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature