Evaluation of the Efficacy and Safety of Inhaled Epoprostenol and Inhaled Nitric Oxide for Refractory Hypoxemia in Patients With Coronavirus Disease 2019.

ABSTRACT:

Objectives

The objectives of this study were to evaluate the efficacy and safety of inhaled epoprostenol and inhaled nitric oxide in patients with refractory hypoxemia secondary to coronavirus disease 2019.

Design

Retrospective single-center study.

Setting

ICUs at a large academic medical center in the United States.

Patients

Thirty-eight adult critically ill patients with coronavirus disease 2019 and refractory hypoxemia treated with either inhaled epoprostenol or inhaled nitric oxide for at least 1 hour between March 1, 2020, and June 30, 2020.

Interventions

Electronic chart review.

Measurements and main results

Of 93 patients screened, 38 were included in the analysis, with mild (4, 10.5%), moderate (24, 63.2%), or severe (10, 26.3%), with acut

SUBMITTER: DeGrado JR 

PROVIDER: S-EPMC7581066 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature