Acute respiratory failure in immunocompromised patients: outcome and clinical features according to neutropenia status.

ABSTRACT:

Background

The impact of neutropenia in critically ill immunocompromised patients admitted in a context of acute respiratory failure (ARF) remains uncertain. The primary objective was to assess the prognostic impact of neutropenia on outcomes of these patients. Secondary objective was to assess etiology of ARF according to neutropenia.

Methods

We performed a post hoc analysis of a prospective multicenter multinational study from 23 ICUs belonging to the Nine-I network. Between November 2015 and July 2016, all adult immunocompromised patients with ARF admitted to the ICU were included in the study. Adjusted analyses included: (1) a hierarchical model with center as random effect; (2) propensity score (PS) matched cohort; and (3) adjusted analysis in the matched cohort.

Res

SUBMITTER: Mokart D 

PROVIDER: S-EPMC7581668 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature