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Prevalence of SARS-CoV-2 antibodies among Swiss hospital workers: Results of a prospective cohort study.

ABSTRACT: In this prospective cohort of 1,012 Swiss hospital employees, 3 different assays were used to screen serum for SARS-CoV-2 antibodies. Seropositivity was 1%; the positive predictive values of the lateral-flow immunoassay were 64% (IgG) and 13% (IgM). History of fever and myalgia most effectively differentiated seropositive and seronegative participants.

SUBMITTER: Kohler PP 

PROVIDER: S-EPMC7582018 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

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Prevalence of SARS-CoV-2 antibodies among Swiss hospital workers: Results of a prospective cohort study.

Kohler Philipp P PP   Kahlert Christian R CR   Sumer Johannes J   Flury Domenica D   Güsewell Sabine S   Leal-Neto Onicio B OB   Notter Julia J   Albrich Werner C WC   Babouee Flury Baharak B   McGeer Allison A   Kuster Stefan S   Risch Lorenz L   Schlegel Matthias M   Vernazza Pietro P  

Infection control and hospital epidemiology 20201008 5

In this prospective cohort of 1,012 Swiss hospital employees, 3 different assays were used to screen serum for SARS-CoV-2 antibodies. Seropositivity was 1%; the positive predictive values of the lateral-flow immunoassay were 64% (IgG) and 13% (IgM). History of fever and myalgia most effectively differentiated seropositive and seronegative participants. ...[more]

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