An injectable self-healing anesthetic glycolipid-based oleogel with antibiofilm and diabetic wound skin repair properties.

ABSTRACT: Globally, wound infections are considered as one of the major healthcare problems owing to the delayed healing process in diabetic patients and microbial contamination. Thus, the development of advanced materials for wound skin repair is of great research interest. Even though several biomaterials were identified as wound healing agents, gel-based scaffolds derived from either polymer or small molecules have displayed promising wound closure mechanism. Herein, for the first time, we report an injectable and self-healing self-assembled anesthetic oleogel derived from glycolipid, which exhibits antibiofilm and wound closure performance in diabetic rat. Glycolipid derived by the reaction of hydrophobic vinyl ester with α-chloralose in the presence of novozyme 435 undergoes spontaneous self-as

SUBMITTER: Prasad YS 

PROVIDER: S-EPMC7582191 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature