Interobserver study on histologic features of idiopathic non-cirrhotic portal hypertension.

ABSTRACT:

Background

Histologic features of idiopathic non-cirrhotic portal hypertension (INCPH) may overlap with those without INCPH. Recently, these features have been recognized as part of the larger spectrum of porto-sinusoidal vascular disease (PSVD). We assessed interobserver agreement on histologic features that are commonly associated with INCPH and studied whether a provision of relevant clinical history improves interobserver agreement.

Methods

The examined histologic features include lobular (such as anisocytosis, nodular regeneration, sinusoidal dilatation, increased parenchymal draining veins, and incomplete fibrous septa) and portal tract changes (such as paraportal shunting vessel(s), portal tract remnant, increased number of portal vessels, and obliterative portal veno

SUBMITTER: Kmeid M 

PROVIDER: S-EPMC7583235 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature