New Insights for BPIFB4 in Cardiovascular Therapy.

ABSTRACT: Aging is the most relevant risk factor for cardiovascular diseases which are the main cause of mortality in industrialized countries. In this context, there is a progressive loss of cardiovascular homeostasis that translates in illness and death. The study of long living individuals (LLIs), which show compression of morbidity toward the end of their life, is a valuable approach to find the key to delay aging and postpone associate cardiovascular events. A contribution to the age-related decline of cardiovascular system (CVS) comes from the immune system; indeed, it is dysfunctional during aging, a process described as immunosenescence and comprises the combination of several processes overpowering both innate and adaptative immune system. We have recently discovered a longevity-associated

SUBMITTER: Dossena M 

PROVIDER: S-EPMC7583974 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature