Coronary flow velocity reserve and inflammatory markers in living kidney donors.

ABSTRACT:

Background

Coronary microvascular dysfunction is prevalent in chronic kidney disease (CKD), and may contribute to the development of myocardial dysfunction in CKD. Coronary flow velocity reserve (CFVR) is a marker of coronary microvascular function and falls with increasing CKD stage. Living kidney donors have renal function consistent with early stage CKD and concern has been raised about their cardiovascular risk. No studies to date have investigated the presence of coronary microvascular dysfunction in living kidney donors.

Methods

25 healthy controls and 23 living kidney donors were recruited and underwent assessment with transthoracic echocardiography, Doppler CFVR, myocardial contrast echocardiography and serum multiplex immunoassay panels.

Results

Doppler CFVR

SUBMITTER: Radhakrishnan A 

PROVIDER: S-EPMC7584109 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature