Race and sex differences in cardiovascular autonomic regulation.

ABSTRACT: Racial and ethnic differences in cardiovascular morbidity and mortality persist despite advances in risk factor identification and implementation of evidence-based treatment strategies. African American men and women are disproportionately affected by cardiovascular risk factors, particularly hypertension. In this context, previous studies have identified sex and racial differences in autonomic cardiovascular regulation which may contribute to the development of hypertension and its high morbidity burden among African Americans. In this review, we provide a comprehensive evaluation of the potential pathophysiological mechanisms of blood pressure control and their differences based on sex and race. These mechanisms include obesity-induced sympathetic activation, sympatho-vascular transducti

SUBMITTER: Farrell MC 

PROVIDER: S-EPMC7584374 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature