SARS-CoV-2 isolation from the first reported patients in Brazil and establishment of a coordinated task network.

ABSTRACT:

Background

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed in Brazil in February 2020, the first cases were followed by an increase in the number of cases throughout the country, resulting in an important public health crisis that requires fast and coordinated responses.

Objectives

The objective of this work is to describe the isolation and propagation properties of SARS-CoV-2 isolates from the first confirmed cases of coronavirus disease 2019 (COVID-19) in Brazil.

Methods

After diagnosis in patients that returned from Italy to the São Paulo city in late February by RT-PCR, SARS-CoV-2 isolates were obtained in cell cultures and characterised by full genome sequencing, electron microscopy and in vitro replication properties.

Findings

T

SUBMITTER: Araujo DB 

PROVIDER: S-EPMC7586445 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature