The association between partner bereavement and melanoma: cohort studies in the U.K. and Denmark.

ABSTRACT:

Background

Psychological stress is commonly cited as a risk factor for melanoma, but clinical evidence is limited.

Objectives

This study aimed to evaluate the association between partner bereavement and (i) first-time melanoma diagnosis and (ii) mortality in patients with melanoma.

Methods

We conducted two cohort studies using data from the U.K. Clinical Practice Research Datalink (1997-2017) and Danish nationwide registries (1997-2016). In study 1, we compared the risk of first melanoma diagnosis in bereaved vs. matched nonbereaved people using stratified Cox regression. In study 2 we estimated hazard ratios (HRs) for death from melanoma in bereaved compared with nonbereaved individuals with melanoma using Cox regression. We estimated HRs separately for the U.K. and

SUBMITTER: Wong AYS 

PROVIDER: S-EPMC7587014 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature