Antiulcerogenic effects of Celosia trigyna plant extracts on ethanol-induced gastric ulcer in adult Wistar rats.

ABSTRACT:

Background and aim

Gastric ulcer is a chronic disease and serious health issue. Celosia trigyna is a medicinal plant used traditionally for wound healing. This study aimed to isolate the bioactive compounds from Celosia trigyna and to investigate the in vitro and in vivo anti-ulcerogenic effects of the extracts on ethanol-induced gastric ulcer on adult Wistar rats to determine their regenerative potential.

Experimental procedure

Seven groups (A - negative control, B - vehicle control, C, D, E, F and G - positive control, n = 5) of five adult Wistar rats received treatment for ethanol-induced gastric ulcer.

Results and conclusion

Phytochemical analysis led to the isolation of chondrillasterol, lutein, pheophytin a and chondrillasterol

SUBMITTER: Ofusori AE 

PROVIDER: S-EPMC7588333 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature