Multivessel versus culprit-only PCI in STEMI patients with multivessel disease: meta-analysis of randomized controlled trials.

ABSTRACT:

Aims

To perform a pairwise meta-analysis of randomized controlled trials (RCTs) comparing multivessel percutaneous coronary intervention (PCI) and culprit vessel-only PCI in ST-elevation myocardial infarction (STEMI) patients without cardiogenic shock.

Methods

We searched MEDLINE, Cochrane Central Register of Controlled Trials, and Embase for RCTs comparing multivessel PCI with culprit vessel-only PCI in STEMI patients without cardiogenic shock and multivessel coronary artery disease. Only RCTs reporting mortality or myocardial reinfarction after at least 6 months following randomization were included. Hazard ratios (HRs) were pooled using random-effect models.

Results

Nine RCTs were included in the final analysis. In total, 523 (8.3%) of 6314 patients suffered the co

SUBMITTER: Feistritzer HJ 

PROVIDER: S-EPMC7588388 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature