Optimizing diastolic pressure gradient assessment.

ABSTRACT:

Aims

The diastolic pressure gradient (DPG) has been proposed as a marker pulmonary vascular disease in the setting of left heart failure (HF). However, its diagnostic utility is compromised by the high prevalence of physiologically incompatible negative values (DPG_NEG) and the contradictory evidence on its prognostic value. Pressure pulsatility impacts on DPG measurements, thus conceivably, pulmonary artery wedge pressure (PAWP) measurements insusceptible to the oscillatory effect of the V-wave might yield a more reliable DPG assessment. We set out to investigate how the instantaneous PAWP at the trough of the Y-descent (PAWP_Y) influences the prevalence of DPG_NEG and the prognostic value of the resultant DPG_Y.

Methods

Hundred and f

SUBMITTER: Manouras A 

PROVIDER: S-EPMC7588394 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature