Prediction of rupture risk in cerebral aneurysms by comparing clinical cases with fluid-structure interaction analyses.

ABSTRACT: Cerebral aneurysms should be treated on the basis of accurate rupture risk prediction. Nowadays, the rupture risk in aneurysms has been estimated using hemodynamic parameters. In this paper, we suggest a new way to predict the rupture risks in cerebral aneurysms by using fluid-structure interaction (FSI) analysis for better decision-making regarding treatment. A patient-specific model was constructed using digital subtraction angiography of 51 cerebral aneurysms. For each model, a thin-walled area (TWA) was first predicted using computational fluid dynamics (CFD), and then the highest equivalent strain in the TWA was calculated with FSI by varying wall thicknesses and mechanical properties. A critical curve was made from 16 FSI results for each patient-specific model to estimate the ruptur

SUBMITTER: Cho KC 

PROVIDER: S-EPMC7588470 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature